June 16-20, 2013

Leipzig, Germany

Presentation Details

Name: Application Talks
Applications of UT-Heart Multiscale Heart Simulator on K Computer
Time: Monday, June 17, 2013
4:15 PM - 4:40 PM
Room:   Hall 3
CCL - Congress Center Leipzig
Speakers:   Takumi Washio, University of Tokyo
Abstract:   In this talk, we introduce the multiscale heart simulation tool that integrates the three scale phenomena from the microscopic stochastic sarcomere kinetics to the macroscopic heart beat via the mesoscopic myocardial cell assembly.
In the sarcomere kinetics, the stochastic behaviors of the myosin heads in the cooperative cross bridge cycling are directly simulated by the Monte Carlo (MC) simulations. This stochastic sarcomere model is coupled with the contractile myofibril elements in the finite element (FE) cell assembly model. The cell assembly model is further coupled with the macroscopic finite element heart model by means of the homoginization method. Some interesting simulation results on K computer are introduced to show the purposes of such a simulation tool in physiological research area.
Program may be subject to changes.