|Name:||Application TalksApplications of UT-Heart Multiscale Heart Simulator on K Computer|
|Time:||Monday, June 17, 2013
4:15 PM - 4:40 PM
CCL - Congress Center Leipzig
|Speakers:||Takumi Washio, University of Tokyo|
|Abstract:||In this talk, we introduce the multiscale heart simulation tool that integrates the three scale phenomena from the microscopic stochastic sarcomere kinetics to the macroscopic heart beat via the mesoscopic myocardial cell assembly.
In the sarcomere kinetics, the stochastic behaviors of the myosin heads in the cooperative cross bridge cycling are directly simulated by the Monte Carlo (MC) simulations. This stochastic sarcomere model is coupled with the contractile myofibril elements in the finite element (FE) cell assembly model. The cell assembly model is further coupled with the macroscopic finite element heart model by means of the homoginization method. Some interesting simulation results on K computer are introduced to show the purposes of such a simulation tool in physiological research area.